Chandrasekhar, Srivari ; Kiran Babu, G. S. ; Mohapatra, Debendra K. (2011) Practical syntheses of (2S)-R207910 and (2R)-R207910 European Journal of Organic Chemistry, 2011 (11). pp. 2057-2061. ISSN 1434-193X
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Official URL: http://onlinelibrary.wiley.com/doi/10.1002/ejoc.20...
Related URL: http://dx.doi.org/10.1002/ejoc.201001720
Abstract
Concise and practical syntheses of (2S)-R207910 (3a) and (2R)-R207910 (3b) have been achieved in high overall yield of 12% in 10 steps for each isomer starting from a known intermediate following Sharpless asymmetric epoxidation, regioselective epoxide opening, modified allylzinc bromide addition as key reactions.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to John Wiley and Sons. |
| Keywords: | Medicinal Chemistry; Tuberculosis; Total Synthesis; Asymmetric Synthesis; Epoxidation |
| ID Code: | 62323 |
| Deposited On: | 22 Sep 2011 03:38 |
| Last Modified: | 22 Sep 2011 03:38 |
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