Photoinduced DNA and protein cleavage activity of ferrocene-appended L-methionine reduced schiff base copper(II) complexes of phenanthroline bases

Goswami, Tridib K. ; Roy, Mithun ; Nethaji, Munirathinam ; Chakravarty, Akhil R. (2009) Photoinduced DNA and protein cleavage activity of ferrocene-appended L-methionine reduced schiff base copper(II) complexes of phenanthroline bases Organometallics, 28 (7). pp. 1992-1994. ISSN 0276-7333

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Official URL: http://pubs.acs.org/doi/abs/10.1021/om900012b

Related URL: http://dx.doi.org/10.1021/om900012b

Abstract

Ferrocene-appended ternary copper(II) complexes of phenanthroline bases having CuN3OS coordination with an axial Cu-S bond derived from l-methionine reduced Schiff base shows red light induced oxidative DNA cleavage activity following a hydroxyl radical pathway. The dipyridophenazine complex, in addition, displays photoinduced oxidative cleavage of bovine serum albumin protein in UV-A light.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:6145
Deposited On:19 Oct 2010 11:04
Last Modified:23 May 2011 05:39

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