Synthesis and utilisation of chiral 3-hydroxy perhydropyrrolo [2,1-c] [1,4] oxazin-4-one as a novel precursor for the enantioselective synthesis of α-hydroxy carboxylic acids

Pandey, Ganesh ; Das, Parthasarathi ; Reddy, Paidi Y. (1998) Synthesis and utilisation of chiral 3-hydroxy perhydropyrrolo [2,1-c] [1,4] oxazin-4-one as a novel precursor for the enantioselective synthesis of α-hydroxy carboxylic acids Tetrahedron Letters, 39 (39). pp. 7153-7154. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(98)01530-5

Abstract

A novel strategy for the enantioselective synthesis of several a-hydroxy carboxylic acids by the nucleophilic alkylation of chiral 3-hydroxy-(3S, 8aS)-perhydropyrrolo [2,1-C] [1,4] oxazin -4 one is reported.

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Deposited On:13 Sep 2011 11:27
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