Iodine-catalyzed coupling of 4-hydroxyproline with isatins: an expeditious synthesis of 3-pyrrolyl indolin-2-ones

Yadav, J. S. ; Subba Reddy, B. V. ; Jain, Ruchi ; Subba Reddy, U. V. (2007) Iodine-catalyzed coupling of 4-hydroxyproline with isatins: an expeditious synthesis of 3-pyrrolyl indolin-2-ones Journal of Molecular Catalysis A: Chemical, 278 (1-2). pp. 38-41. ISSN 1381-1169

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.molcata.2007.08.005

Abstract

Molecular iodine is found to catalyze efficiently the coupling of 4-hydroxyproline with isatins under mild conditions to produce 3-(1H-pyrrol-1-yl)indolin-2-one and 11-(1H-pyrrol-1-yl)-11H-indeno[1,2-b]quinoxalin-11-one derivatives in excellent yields in a short reaction time with high selectivity. The use of iodine makes this procedure quite simple, more convenient and cost-effective.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Pyrrole; Isatins; Molecular Iodine; Indolinone; Quinoxaline
ID Code:60414
Deposited On:09 Sep 2011 03:55
Last Modified:09 Sep 2011 03:55

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