Yadav, J. S. ; Reddy, B. V. S. ; Sreenivas, M. ; Sathaiah, K. (2005) Facile addition of alkynes to aza-aromatic systems: a new protocol for the preparation of 2-alkynyl-1,2-dihydroquinolines Tetrahedron Letters, 46 (51). pp. 8905-8908. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2005.10.101
Abstract
1-Alkynes undergo smooth addition to activated quinolines, isoquinolines and pyridines in the presence of copper iodide/iPr2NEt under extremely mild conditions to afford 2-alkynyl-1,2-dihydroquinolines in excellent yields with high selectivity. This method is also useful for functionalization of monocyclic pyridines.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
Keywords: | Aza-aromatic Compounds; Alkynylation; 2-alkynyl Quinolines |
ID Code: | 60386 |
Deposited On: | 09 Sep 2011 03:54 |
Last Modified: | 09 Sep 2011 03:54 |
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