Joshi, J. B. ; Sawant, S. B. ; Patwardhan, A. W. ; Patil, D. J. ; Kshatriya, S. S. ; Nere, N. K. (2001) Relation between flow pattern and de-activation of enzymes in stirred reactors Chemical Engineering Science, 56 (2). pp. 443-452. ISSN 0009-2509
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0009-2509(00)00247-5
Abstract
Enzymes and microbial cells are increasingly being used for a variety of biochemical transformations. During the process the enzymes/micro-organisms are subjected to hydrodynamic stresses which can lead to their de-activation. This has enormous economic impact due to their high cost. In the present work, attempts have been made to relate the extent of de-activation with the hydrodynamic stresses produced in impeller stirred reactors. The hydrodynamic stresses produced by a variety of impellers have been compared. The extent of de-activation of cellulase enzyme has been co-related with the average hydrodynamic stress within the stirred reactor.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Stirred Reactors; CFD; Enzyme De-activation; Turbulent Stresses |
| ID Code: | 60149 |
| Deposited On: | 08 Sep 2011 09:48 |
| Last Modified: | 08 Sep 2011 09:48 |
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