Utility of pandemic H1N1 2009 influenza virus recombinant hemagglutinin protein-based enzyme-linked immunosorbent assay for serosurveillance

Arankalle, V. A. ; Virkar, R. G. ; Tandale, B. V. ; Ingle, N. B. (2010) Utility of pandemic H1N1 2009 influenza virus recombinant hemagglutinin protein-based enzyme-linked immunosorbent assay for serosurveillance Clinical and Vaccine Immunology, 17 (9). pp. 1481-1483. ISSN 1556-6811

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Official URL: http://cvi.asm.org/cgi/content/abstract/17/9/1481

Related URL: http://dx.doi.org/10.1128/CVI.00223-10

Abstract

An enzyme-linked immunosorbent assay (ELISA) for the detection of IgG antibodies against the pandemic H1N1 2009 influenza A virus, employing a recombinant hemagglutinin protein of the virus, was compared to the hemagglutination inhibition (HI) test using 783 serum samples. The results showed a concordance of 98.4%, suggesting the utility of the ELISA in serosurveillance. Two hundred sixty-nine (100%) serum samples with an HI titer of ≥ 20 were ELISA reactive.

Item Type:Article
Source:Copyright of this article belongs to American Society for Microbiology.
ID Code:59818
Deposited On:07 Sep 2011 14:45
Last Modified:07 Sep 2011 14:45

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