Non-A, non-B epidemic hepatitis: visualization of virus-like particles in the stool by immune electron microscopy

Sreenivasan, M. A. ; Arankalle, V. A. ; Sehgal, A. ; Pavri, K. M. (1984) Non-A, non-B epidemic hepatitis: visualization of virus-like particles in the stool by immune electron microscopy Journal of General Virology, 65 (5). pp. 1005-1007. ISSN 0022-1317

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Official URL: http://vir.sgmjournals.org/content/65/5/1005.short

Related URL: http://dx.doi.org/10.1099/0022-1317-65-5-1005

Abstract

Acute-phase stool samples collected from hepatitis cases during outbreaks of water-borne epidemic hepatitis were examined by immune electron microscopy (IEM). Spherical virus-like particles (27nm in diameter) were visualized in the stool of a hepatitis patient with serological evidence of non-A, non-B (NANB) hepatitis. The IEM demonstrated serological specificity of the antigen with the patient's own convalescent serum as well as a known pool of NANB hepatitis convalescent sera. It is suggested that these virus-like particles may be the aetiological agent of faeco-orally transmitted NANB epidemic hepatitis in India.

Item Type:Article
Source:Copyright of this article belongs to Society for General Microbiology.
Keywords:Hepatitis; non-A, non-B; Electron Microscopy
ID Code:59757
Deposited On:07 Sep 2011 14:31
Last Modified:07 Sep 2011 14:31

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