Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992

Arankalle, Vidya A. ; Tsarev, Sergei A. ; Chadha, Mandeep S. ; Alling, David W. ; Emerson, Suzanne U. ; Banerjee, Kalyan ; Purcell, Robert H. (1995) Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992 The Journal of Infectious Diseases, 171 (2). pp. 447-450. ISSN 0022-1899

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Official URL: http://jid.oxfordjournals.org/content/171/2/447.sh...

Related URL: http://dx.doi.org/10.1093/infdis/171.2.447

Abstract

The age-specific seroprevalence of antibody to hepatitis A virus (HAV) and antibody to hepatitis E virus (HEV) were studied in persons in Pune, India, where both viruses are endemic. The data showed that HAV infected the majority of persons by age 3 years and virtually 100% by late childhood. In contrast, infection with HEV was rare in children and did not reach peak prevalence (33%-40%) until early adulthood. The reason for the differences in infection rates between HAV and HEV is not known. Age-specific antibody patterns in serum samples obtained 10 years apart show that neither HAV nor HEV has diminished in medical importance in this Indian community.

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