Subba Reddy, B. V. ; Bhavani, K. ; Raju, A. ; Yadav, J. S. (2011) A novel trifunctional organocatalyst for the asymmetric aldol reaction: a facile enantioselective synthesis of β-hydroxyketones Tetrahedron: Asymmetry, 22 (8). pp. 881-886. ISSN 0957-4166
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetasy.2011.05.001
Abstract
A new L-prolinamide trifunctional catalyst has been developed for the enantioselective aldol reaction of various aromatic and aliphatic aldehydes with acetone. This method provides high yields of β-hydroxyketones (up to 90%) with good enantioselectivity (up to 92%) at a low catalyst loading (10 mol %).
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
ID Code: | 59614 |
Deposited On: | 07 Sep 2011 05:59 |
Last Modified: | 07 Sep 2011 05:59 |
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