Yadav, J. S. ; Subba Reddy, B. V. ; Madhusudhan Reddy, G. ; Narasimha Chary, D. (2007) Three component, regioselective, one-pot synthesis of β-hydroxytriazoles from epoxides via 'click reactions' Tetrahedron Letters, 48 (49). pp. 8773-8776. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.09.160
Abstract
2-Azidoalcohols derived in situ from epoxides and sodium azide undergo smooth coupling with alkynes under neutral conditions by means of 'click reactions' to furnish β-hydroxytriazoles in excellent yields and with high regioselectivity. This reaction proceeds smoothly in water at room temperature without the need for acid catalysis.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
Keywords: | Epoxides; 2-azidoalcohols; Alkynes; Click Reaction; Triazoles |
ID Code: | 59588 |
Deposited On: | 07 Sep 2011 05:47 |
Last Modified: | 07 Sep 2011 05:47 |
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