Indium-mediated facile cleavage of the t-butoxycarbonyl group from di-t-butylimidodicarbonate

Yadav, J. S. ; Reddy, B. V. S. ; Srinivasa Reddy, K. ; Bhaskar Reddy, K. (2002) Indium-mediated facile cleavage of the t-butoxycarbonyl group from di-t-butylimidodicarbonate Tetrahedron Letters, 43 (8). pp. 1549-1551. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(01)02374-7

Abstract

Di-t-butylimidodicarbonates are selectively and efficiently deprotected to the corresponding mono-BOC protected amines in high yields using indium or zinc metal in refluxing methanol. Simple BOC and CBz protected amines are unaffected by these conditions.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Indium; Carbamates; Sulfonamides; α-amino Acids
ID Code:59576
Deposited On:07 Sep 2011 05:31
Last Modified:07 Sep 2011 05:31

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