Sabitha, Gowravaram ; Srinivas Reddy, Ch. ; Yadav, J. S. (2006) Total syntheses of the highly potent anti-cancer polyacetylenes, (S)-18-hydroxyminquartynoic acid, (S)-minquartynoic acid and (E)-15,16-dihydrominquartynoic acid Tetrahedron Letters, 47 (26). pp. 4513-4516. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2006.03.118
Abstract
The total syntheses of three polyacetylenic natural products, (S)-18-hydroxyminquartynoic acid (1), (S)-minquartynoic acid (2) and (E)-15,16-dihydrominquartynoic acid (3), has been achieved. The Cadiot-Chodkiewicz cross-coupling reaction was used as the key step for the construction of tetrayne and triyne units.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Natural Products; Polyacetylenes; Cadiot-Chodkiewicz Coupling; Anti-cancer Activity; Anti-HIV Activity |
| ID Code: | 59562 |
| Deposited On: | 07 Sep 2011 05:42 |
| Last Modified: | 07 Sep 2011 05:42 |
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