The first stereo selective total synthesis of (3R),(5R)-5-hydroxy-de-O-methyllasiodiplodin and its epimer via an RCM protocol

Yadav, J. S. ; Das, Saibal ; Satyanarayana Reddy, J. ; Thrimurtulu, N. ; Prasad, A. R. (2010) The first stereo selective total synthesis of (3R),(5R)-5-hydroxy-de-O-methyllasiodiplodin and its epimer via an RCM protocol Tetrahedron Letters, 51 (31). pp. 4050-4052. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2010.05.115

Abstract

The first total synthesis of (3R),(5R)-5-hydroxy-de-O-methyllasiodiplodin and its epimer is reported from malic acid. The adopted approach is highly convergent and stereoselective. The strategy utilizes syn selective reduction and ring-closing metathesis as key steps.

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ID Code:59551
Deposited On:07 Sep 2011 05:58
Last Modified:07 Sep 2011 05:58

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