An efficient synthesis of (+)-prelactone B

Yadav, J. S. ; Bhaskar Reddy, K. ; Sabitha, G. (2004) An efficient synthesis of (+)-prelactone B Tetrahedron Letters, 45 (34). pp. 6475-6476. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2004.06.121

Abstract

An enantioselective synthesis of (+)-prelactone B 1 has been achieved on a multigram scale starting from a known bicyclic precursor 2. The key feature of the strategy is the generation of 3-stereogenic centres from a single bicyclic precursor, which has been utilized as a chiral building block for the synthesis of various natural products.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Prelactone B; Bicyclic Precursor; Streptomyces griseus; Bafilomycin
ID Code:58958
Deposited On:02 Sep 2011 03:19
Last Modified:02 Sep 2011 03:19

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