Yadav, J. S. ; Bhaskar Reddy, K. ; Sabitha, G. (2004) An efficient synthesis of (+)-prelactone B Tetrahedron Letters, 45 (34). pp. 6475-6476. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2004.06.121
Abstract
An enantioselective synthesis of (+)-prelactone B 1 has been achieved on a multigram scale starting from a known bicyclic precursor 2. The key feature of the strategy is the generation of 3-stereogenic centres from a single bicyclic precursor, which has been utilized as a chiral building block for the synthesis of various natural products.
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
Keywords: | Prelactone B; Bicyclic Precursor; Streptomyces griseus; Bafilomycin |
ID Code: | 58958 |
Deposited On: | 02 Sep 2011 03:19 |
Last Modified: | 02 Sep 2011 03:19 |
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