Yadav, J. S. ; Subba Reddy, B. V. ; Chandrakanth, D. ; Satheesh, G. (2007) The first example of the C-3 alkylation of indoles with cyclopropyl ketones promoted by CeCl3·7H2O/LiI Tetrahedron Letters, 48 (45). pp. 8040-8042. ISSN 0040-4039
Full text not available from this repository.
Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.09.023
Abstract
Indoles undergo smooth alkylation with cyclopropyl ketones in the presence of the CeCl3·7H2O/LiI reagent system in refluxing acetonitrile under neutral conditions to produce the corresponding C-3 substituted indole derivatives in good to high yields and with high selectivity. The use of CeCl3·7H2O/LiI makes this method simple, convenient, and cost-effective.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Indoles; Cerium(III) Compounds; Activated Cyclopropanes; C-3 Alkylation |
| ID Code: | 58952 |
| Deposited On: | 02 Sep 2011 03:28 |
| Last Modified: | 02 Sep 2011 03:28 |
Repository Staff Only: item control page
