The first example of the C-3 alkylation of indoles with cyclopropyl ketones promoted by CeCl3·7H2O/LiI

Yadav, J. S. ; Subba Reddy, B. V. ; Chandrakanth, D. ; Satheesh, G. (2007) The first example of the C-3 alkylation of indoles with cyclopropyl ketones promoted by CeCl3·7H2O/LiI Tetrahedron Letters, 48 (45). pp. 8040-8042. ISSN 0040-4039

Full text not available from this repository.

Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.09.023

Abstract

Indoles undergo smooth alkylation with cyclopropyl ketones in the presence of the CeCl3·7H2O/LiI reagent system in refluxing acetonitrile under neutral conditions to produce the corresponding C-3 substituted indole derivatives in good to high yields and with high selectivity. The use of CeCl3·7H2O/LiI makes this method simple, convenient, and cost-effective.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Indoles; Cerium(III) Compounds; Activated Cyclopropanes; C-3 Alkylation
ID Code:58952
Deposited On:02 Sep 2011 03:28
Last Modified:02 Sep 2011 03:28

Repository Staff Only: item control page