Sc(OTf)3-catalyzed alkylation of indoles with propargyl alcohols: an expeditious synthesis of 3-substituted indoles

Yadav, J. S. ; Subba Reddy, B. V. ; Raghavendra Rao, K. V. ; Narayana Kumar, G. G. K. S. (2007) Sc(OTf)3-catalyzed alkylation of indoles with propargyl alcohols: an expeditious synthesis of 3-substituted indoles Tetrahedron Letters, 48 (31). pp. 5573-5576. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2007.04.056

Abstract

Indoles undergo smooth alkylation with propargylic alcohols in the presence of 10 mol % of scandium triflate under mild conditions to produce 3-propargylated indoles in excellent yields with high selectivity.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Scandium(III) Triflate; Propargyl Alcohols; Indoles; Alkylation
ID Code:58900
Deposited On:02 Sep 2011 03:27
Last Modified:02 Sep 2011 03:27

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