Gallium iodide/iodine as a versatile reagent for the aza-Prins cyclization: an expeditious synthesis of 4-iodopiperidines

Yadav, J. S. ; Subba Reddy, B. V. ; Chaya, D. N. ; Narayana Kumar, G. G. K. S. ; Aravind, S. ; Kunwar, A. C. ; Madavi, C. (2008) Gallium iodide/iodine as a versatile reagent for the aza-Prins cyclization: an expeditious synthesis of 4-iodopiperidines Tetrahedron Letters, 49 (20). pp. 3330-3334. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2008.03.006

Abstract

4-Iodopiperidines are prepared in good yields and with high selectivity by means of aza-Prins-cyclization using a catalytic amount of gallium(III) iodide and a stoichiometric amount of iodine under mild reaction conditions. This is the first report on the preparation of 4-iodopiperidines via aza-Prins-cyclization.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:aza-Prins-cyclization; Molecular Iodine; Homoallylic Amines; 4-iodopiperidine
ID Code:58878
Deposited On:02 Sep 2011 03:30
Last Modified:09 Oct 2011 10:44

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