Yadav, J. S. ; Subba Reddy, B. V. ; Hara Gopal, A. V. ; Narayana Kumar, G. G. K. S. ; Madavi, C. ; Kunwar, A. C. (2008) Iodine as a mild and versatile reagent for the synthesis of 1,3-dioxane derivatives via the Prins reaction Tetrahedron Letters, 49 (28). pp. 4420-4423. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2008.05.014
Abstract
Iodine is found to be an effective reagent for the cross-coupling of olefins with aldehydes under mild conditions to produce 4-substituted 1,3-dioxane derivatives in excellent yields and in short reaction times with high selectivity. The use of iodine makes this procedure simple, convenient, cost-effective and practical. This method works not only with formaldehyde but also with acetaldehyde, propionaldehyde and cyclohexanecarboxaldehyde.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Prins Reaction; Molecular Iodine; Olefins; 1,3-dioxane |
| ID Code: | 58851 |
| Deposited On: | 02 Sep 2011 03:31 |
| Last Modified: | 02 Sep 2011 03:31 |
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