Yadav, J. S. ; Sridhar Reddy, M. ; Prasad, A. R. (2005) A convergent route to β-hydroxy δ-lactones through Prins cyclisation as the key step: synthesis of (+)-prelactones B, C and V Tetrahedron Letters, 46 (12). pp. 2133-2136. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2005.01.121
Abstract
Reactions of homoallylic alcohols with aldehydes in the presence of acid catalysts gave multisubstituted tetrahydropyrans with the creation of one to three new stereogenic centres in a single-pot process. The utility of this approach is extended to the enantioselective syntheses of (+)-prelactones B, C and V.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Prins Cyclisation; δ-lactones; Homoallylic Alcohol; Tetrahydropyrans |
| ID Code: | 58772 |
| Deposited On: | 02 Sep 2011 03:21 |
| Last Modified: | 02 Sep 2011 03:21 |
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