Enantioselective reduction of 2-substituted tetrahydropyran-4-ones using Daucus carota plant cells

Yadav, J. S. ; Subba Reddy, B. V. ; Sreelakshmi, Ch. ; Narayana Kumar, G. G. K. S. ; Bhaskar Rao, A. (2008) Enantioselective reduction of 2-substituted tetrahydropyran-4-ones using Daucus carota plant cells Tetrahedron Letters, 49 (17). pp. 2768-2771. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2008.02.131

Abstract

Enzymatic reduction of 2-substituted tetrahydropyran-4-ones with Daucus carota, plant cells as biocatalyst occurred in water under extremely mild and environmentally benign conditions giving a 1:1 mixture of diastereoselectively (2R,4S)- and (2S,4S)-2-aryl- or 2-alkyl-tetrahydropyranols in high yields.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:Biocatalytic Transformation; Carrot Root; Enantioselective Reduction; Chiral Tetrahydropyranols
ID Code:58745
Deposited On:02 Sep 2011 03:30
Last Modified:02 Sep 2011 03:30

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