Short oligodeoxynucleotides with d(G-C)n sequence do not assume left-handed conformation in high salt conditions

Quadrifoglio, Franco ; Manzini, Giorgio ; Yathindra, Narayanarao (1984) Short oligodeoxynucleotides with d(G-C)n sequence do not assume left-handed conformation in high salt conditions Journal of Molecular Biology, 175 (3). pp. 419-423. ISSN 0022-2836

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Official URL: http://www.sciencedirect.com/science/article/pii/0...

Related URL: http://dx.doi.org/10.1016/0022-2836(84)90358-9

Abstract

d(G-C)n oligodeoxynucleotides (with n varying from 3 to 7) were studied by the circular dichroism technique in 5 M -NaCl. Contrary to what was previously found with the d(C-G)n series in the same solvent, the left-handed double-stranded Z-conformation appears less stable than the B-form for low n values. The influence of base sequence on the relative stability of B- and Z-conformations for the two series is discussed.

Item Type:Article
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ID Code:58681
Deposited On:02 Sep 2011 03:47
Last Modified:02 Sep 2011 03:47

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