Synthesis of functionalised bicyclic α-methylene-γ-butyrolactones from 2, 3-cyclohexene acetal via radical cyclisation approach

Vankar, Yashwant D. ; Chaudhuri, Narayan C. (1991) Synthesis of functionalised bicyclic α-methylene-γ-butyrolactones from 2, 3-cyclohexene acetal via radical cyclisation approach Synthetic Communications, 21 (7). pp. 885-899. ISSN 0039-7911

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Official URL: http://www.tandfonline.com/doi/abs/10.1080/0039791...

Related URL: http://dx.doi.org/10.1080/00397919108019773

Abstract

2, 3-Cyclohexene acetal, wherein the acetal wherein the acetal lunctionality is derived from 2R, 3R(+)-tartaric acid, has been transformed regioselectively into functionalised bicyclic α-methylene-γ-butyrolactoes via radical cyclisations. The radicals were derived from n-bu3SnH reactions with secondary bromides and a tertiary nitro compound.

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