John Pal, A. P. ; Vankar, Yashwant D. (2010) Azidation of anomeric nitro sugars: application in the synthesis of spiroaminals as glycosidase inhibitors Tetrahedron Letters, 51 (18). pp. 2519-2524. ISSN 0040-4039
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/j.tetlet.2010.03.003
Abstract
6,5-Fused sugar-derived spiroaminals have been synthesized from the azido esters obtained via the nucleophilic substitution reactions of unstable Michael adducts derived from 1-nitro sugars. Most of the spiroaminals synthesized showed moderate but selective inhibitory activities toward some glycosidases.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Nitro Sugars; Hydrolysis; Azidation; Spiroaminals; Glycosidase Inhibitors |
| ID Code: | 58291 |
| Deposited On: | 31 Aug 2011 06:42 |
| Last Modified: | 31 Aug 2011 06:42 |
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