Highly stereoselective prins cyclization of silylmethyl-substituted cyclopropyl carbinols to 2, 4, 6-trisubstituted tetrahydropyrans

Yadav, Veejendra K. ; Kumar, Naganaboina Vijaya (2004) Highly stereoselective prins cyclization of silylmethyl-substituted cyclopropyl carbinols to 2, 4, 6-trisubstituted tetrahydropyrans Journal of the American Chemical Society, 126 (28). pp. 8652-8653. ISSN 0002-7863

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Official URL: http://pubs.acs.org/doi/abs/10.1021/ja048000c

Related URL: http://dx.doi.org/10.1021/ja048000c

Abstract

The homoallyl cation formed from a cyclopropyl carbinol that was vicinally substituted by a silylmethyl function underwent smooth Prins cyclization with aldehydes and ketones to form 2,4,6-trisubstituted tetrahydropyrans with very high stereoselectivity.

Item Type:Article
Source:Copyright of this article belongs to American Chemical Society.
ID Code:58210
Deposited On:31 Aug 2011 06:56
Last Modified:31 Aug 2011 06:56

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