Cyclopentane synthesis and annulation: intramolecular radical cyclization of acetals

Yadav, Veejendra K. ; Fallis, Alex G. (1988) Cyclopentane synthesis and annulation: intramolecular radical cyclization of acetals Tetrahedron Letters, 29 (8). pp. 897-900. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(00)82476-4

Abstract

A general procedure for cyclopentane synthesis based on free-radical cyclization of thioacetals is described. This permits the rapid assembly, by intramolecular annulation, of various ring systems bearing useful functionality for use in total synthesis. Radical cyclization of unsaturated thioacetals affords functionalized cyclopentanes.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
ID Code:58206
Deposited On:31 Aug 2011 06:50
Last Modified:31 Aug 2011 06:50

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