Total synthesis of (+)-lentiginosine from D-glucose

Alam, Mohammad Abrar ; Vankar, Yashwant D. (2008) Total synthesis of (+)-lentiginosine from D-glucose Tetrahedron Letters, 49 (38). pp. 5534-5536. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/j.tetlet.2008.07.057

Abstract

A total synthesis of (+)-lentiginosine, a potent and selective amyloglucosidase inhibitor, is reported from a D-glucose-derived epoxide in 38% overall yield. In this synthesis, ambient conditions and readily available starting materials and reagents are used.

Item Type:Article
Source:Copyright of this article belongs to Elsevier Science.
Keywords:(+)-Lentiginosine; D-Glucose; Epoxide; Barton Deoxygenation
ID Code:58190
Deposited On:31 Aug 2011 06:41
Last Modified:31 Aug 2011 06:41

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