A novel pseudo four component reaction involving homoenolate for the synthesis of γ-aminobutyric acid (GABA) derivatives

Nair, Vijay ; Varghese, Vimal ; Babu, Beneesh P. ; Sinu, C. R. ; Suresh, Eringathodi (2010) A novel pseudo four component reaction involving homoenolate for the synthesis of γ-aminobutyric acid (GABA) derivatives Organic and Biomolecular Chemistry, 8 (4). pp. 761-764. ISSN 1477-0520

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Official URL: http://pubs.rsc.org/en/Content/ArticleLanding/2010...

Related URL: http://dx.doi.org/10.1039/B922981G

Abstract

Homoenolate generated from α,β-unsaturated aldehydes by NHC catalysis underwent facile addition to conjugated sulfonimines, generated in situ, and subsequent methanolysis to afford protected GABA derivatives stereoselectively and in high yields, thus constituting a novel pseudo four component reaction.

Item Type:Article
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ID Code:58042
Deposited On:31 Aug 2011 12:49
Last Modified:31 Aug 2011 12:49

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