A novel three-component reaction for the diastereoselective synthesis of 2H-pyrimido [2, 1-a] isoquinolines via 1, 4-dipolar cycloaddition

Nair, Vijay ; Sreekanth, A. R. ; Abhilash, N. ; Bhadbhade, Mohan M. ; Gonnade, Rajesh C. (2002) A novel three-component reaction for the diastereoselective synthesis of 2H-pyrimido [2, 1-a] isoquinolines via 1, 4-dipolar cycloaddition Organic Letters, 4 (21). pp. 3575-3577. ISSN 1523-7060

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Official URL: http://pubs.acs.org/doi/abs/10.1021/ol0264004

Related URL: http://dx.doi.org/10.1021/ol0264004

Abstract

The 1,4-dipole derived from isoquinoline and DMAD has been shown to react readily with N-tosylimines resulting in the diastereoselective synthesis of 2H-pyrimido[2,1-a]isoquinoline derivatives.

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Deposited On:31 Aug 2011 12:44
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