Studies on some electrophilic substitution reactions in the furan series: the synthesis of 2,4-disubstituted furans

Kutney, J. P. ; Hanssen, H. W. ; Vijayakumaran Nair, G. (1971) Studies on some electrophilic substitution reactions in the furan series: the synthesis of 2,4-disubstituted furans Tetrahedron, 27 (15). pp. 3323-3330. ISSN 0040-4020

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4020(01)97744-0

Abstract

An investigation of several electrophilic substitution reactions on 3-methylfuran is reported. Friedel-Crafts acylation of 3-methylfuran with acetyl and propionyl chlorides yielded both 2,3- and 2,4-disubstituted furans. Vilsmeier and Gatterman formylation procedures yielded 3-methylfurfural and 4-methylfurfural while mercuration appeared to yield only the 2,3-disubstituted derivative.

Item Type:Article
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ID Code:58000
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