Parthasarathy, Sugumar ; Vishwanath, Tukaram Jadhav ; Mukhulesh, Gatne ; Dev, Chandran ; Narasu, Mangamoori Lakshmi ; Narasimhan, Rangarajan Pundi ; Alwar, Srinivasan Villuppanoor (2010) Assessment of immunoprophylactic efficacy of recombinant mid gut antigen (Bm95) of Rhiphicephalus microplus in Bos indicus Current Trends in Biotechnology and Pharmacy, 4 (4). No pp. given. ISSN 0973-8916
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Official URL: http://www.indianjournals.com/ijor.aspx?target=ijo...
Abstract
Use of recombinant Bm95 isolated from an Argentinean strain of Rhiphicephalus microplus A as a vaccine candidate to control the tick infestation in India was investigated. Recombinant Bm95 expressed in yeast, Pichia pastoris. Purified protein blended into a vaccine using aluminium hydroxide as an adjuvant. An adverse effect on the reproduction of ticks was observed in vaccinated animals indicating reduced the environmental contamination and source of infestation indicating its use of Bm95 in the immunological control of ticks in India.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Association of Biotechnology and Pharmacy. |
| Keywords: | Tick; Bm95; Rhiphicephalus; Tickborne Diseases |
| ID Code: | 57899 |
| Deposited On: | 30 Aug 2011 07:51 |
| Last Modified: | 30 Aug 2011 07:51 |
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