Saha, Sougata ; Murthy, Sreenivasa ; Rangarajan, Pundi N. (2006) Identification and characterization of a virus-inducible non-coding RNA in mouse brain Journal of General Virology, 87 (7). pp. 1991-1995. ISSN 0022-1317
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Official URL: http://vir.sgmjournals.org/cgi/content/abstract/87...
Related URL: http://dx.doi.org/10.1099/vir.0.81768-0
Abstract
Infection of mice with Japanese encephalitis virus or Rabies virus results in the activation of a gene encoding a novel, non-coding RNA (ncRNA) in the mouse central nervous system. This transcript, named virus-inducible ncRNA (VINC), is identical to a 3.18 kb transcript expressed in mouse neonate skin (GenBank accession no. AK028745 [GenBank] ) that, together with a number of unannotated cDNAs and expressed sequence tags, is grouped in the mouse unigene cluster Mm281895. VINC is expressed constitutively in early mouse embryo and several adult non-neuronal mouse tissues, as well as a murine renal adenocarcinoma (RAG) cell line. Northern blotting of nuclear and cytoplasmic RNAs revealed that VINC is localized primarily in the nucleus of RAG cells and is thus a novel member of the nuclear ncRNA family.
Item Type: | Article |
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Source: | Copyright of this article belongs to Society for General Microbiology. |
ID Code: | 57863 |
Deposited On: | 30 Aug 2011 07:50 |
Last Modified: | 30 Aug 2011 07:50 |
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