Histopathological changes following the use of biological and synthetic glue for dural grafts: an experimental study

Agarwal, A. ; Varma, A. ; Sarkar, C. (1998) Histopathological changes following the use of biological and synthetic glue for dural grafts: an experimental study British Journal of Neurosurgery, 12 (3). pp. 213-216. ISSN 0268-8697

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Official URL: http://informahealthcare.com/doi/abs/10.1080/02688...

Related URL: http://dx.doi.org/10.1080/02688699845014

Abstract

Dural defects and CSF leaks are common neurosurgical problems and the search for a suitable sealant continues. The effects of such sealants on meninges and brain have not been previously studied. To study the effect of two commonly used sealants, burrholes were made in 20 rats, with the creation of dural tears which were covered with human cadaveric dura smeared with synthetic (cyanoacrylate) glue and gelatine (GRG) glue. Plain dura, placed in one of the burrholes served as a control. An intense inflammatory reaction was observed with both glues, which was found to persist till the eleventh week.

Item Type:Article
Source:Copyright of this article belongs to Informa plc.
Keywords:Dural Grafts; Gelatine Glue; Synthetic Glue
ID Code:56382
Deposited On:23 Aug 2011 11:30
Last Modified:23 Aug 2011 11:30

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