Bridgehead substitution of 1-methoxybicyclo[2.2.2]oct-5-en-2-one derivatives: towards the synthesis of (±)-allo-cedrol [khusiol]

Sathya Shanker, P. ; Subba Rao, G. S. R. (1994) Bridgehead substitution of 1-methoxybicyclo[2.2.2]oct-5-en-2-one derivatives: towards the synthesis of (±)-allo-cedrol [khusiol] Journal of the Chemical Society, Chemical Communications (5). pp. 621-622. ISSN 0022-4936

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Official URL: http://pubs.rsc.org/en/content/articlelanding/1994...

Related URL: http://dx.doi.org/10.1039/C39940000621

Abstract

Preparation of the key intermediates, 11 and 21, required for the synthesis of (±)-allo-cedrol (khusiol) is reported by a novel methodology involving the substitution at the bridgehead position of 1-methoxybicyclo[2.2.2.]oct-5-en-2-one derivatives.

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