A model synthetic approach towards the furanacetal component of azadirachtin: a potent insect antifeedant

Abstract

In this article, a model synthetic approach towards the furanacetal component of azadirachtin has been described from α-D-glucose. Tandem radical cyclization was the key step for the formation of the desired tricyclic system. The reaction provided a bicyclic system instead of the desired tricyclic molecule. The reason for the unsuccessful tandem cyclization was proposed to be mainly energy factors.