An efficient method for opening nonactivated aziridines with TMS azide: application in the synthesis of chiral 1,2-diaminocyclohexane

Chandrasekhar, M. ; Sekar, G. ; Singh, Vinod K. (2000) An efficient method for opening nonactivated aziridines with TMS azide: application in the synthesis of chiral 1,2-diaminocyclohexane Tetrahedron Letters, 41 (51). pp. 10079-10083. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(00)01793-7

Abstract

A variety of N-substituted aziridines have been opened with TMS azide in MeCN at rt in the absence of any Lewis acid. The reaction was extended to the synthesis of (R,R)- and (S,S)-1,2-diaminocyclohexane.

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Deposited On:18 Aug 2011 08:35
Last Modified:18 Aug 2011 08:35

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