An efficient synthesis of chiral nonracemic diamines: application in asymmetric synthesis

Saravanan, Parthasarathy ; Singh, Vinod K. (1998) An efficient synthesis of chiral nonracemic diamines: application in asymmetric synthesis Tetrahedron Letters, 39 (1-2). pp. 167-170. ISSN 0040-4039

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Official URL: http://www.sciencedirect.com/science/article/pii/S...

Related URL: http://dx.doi.org/10.1016/S0040-4039(97)10578-0

Abstract

A variety of chiral diamines have been synthesized from optically active mandelic acid in an efficient manner. The chiral nonracemic lithium amide base derived from one of the diamines has been used in formal asymmetric synthesis of natural products such as (−)-utenone A and (−)-carbovir.

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