Seroprevalence of neutralizing antibodies to adenovirus type 5 among children in India: implications for recombinant adenovirus-based vaccines

Appaiahgari, Mohan Babu ; Pandey, Ravindra Mohan ; Vrati, Sudhanshu (2007) Seroprevalence of neutralizing antibodies to adenovirus type 5 among children in India: implications for recombinant adenovirus-based vaccines Clinical and Vaccine Immunology, 14 (8). pp. 1053-1055. ISSN 1556-6811

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Official URL: http://cvi.asm.org/cgi/content/abstract/14/8/1053

Related URL: http://dx.doi.org/10.1128/CVI.00173-07

Abstract

We determined the levels of adenovirus 5 (Ad5) neutralizing antibodies in children in India less than 2 years of age. The results clearly show an age-dependent increase in Ad5-specific immunity, with 7- to 12-month-old children having the lowest levels of Ad5 immunity. This opens up the scope for the use of recombinant Ad5-based vaccines in this age group.

Item Type:Article
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Deposited On:18 Aug 2011 07:35
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