Cryptosin - a new cardenolide in tissue culture and intact plants of Cryptolepis buchanani Roem. & Schult

Venkateswara, R. ; Sankara Rao, K. ; Vaidyanathan, C. S. (1987) Cryptosin - a new cardenolide in tissue culture and intact plants of Cryptolepis buchanani Roem. & Schult Plant Cell Reports, 6 (4). pp. 291-293. ISSN 0721-7714

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Official URL: http://www.springerlink.com/content/kv5837514m6323...

Related URL: http://dx.doi.org/10.1007/BF00272001

Abstract

A steroidal glycoside of the digoxin type was isolated from fresh leaves and cultured cells of Cryptolepis buchanani Roem & Schult (Asclepiadaceae). Cultures were raised from leaf and shoot. Explants were cultured on MS medium containing 2,4-D, NAA, BA and coconut milk. Metabolically active calluses were proliferated and maintained on Gamborg's B5 medium with 2,4-D and Kn. The new compound, named cryptosin, was characterised by infrared nmr and mass spectroscopy. Cryptosin was also screened for its pharmacological properties and its cardiotonic action was established.

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