Pandian, M. R. ; Gupta, P. D. ; Talwar, G. P. ; Avrameas, S. (1975) Presence of "receptors" for growth hormone on membranes of the rat thymocytes European Journal of Endocrinology, 78 . pp. 781-790. ISSN 0804-4643
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Official URL: http://www.eje-online.org/content/78/4/781.abstrac...
Related URL: http://dx.doi.org/10.1530/acta.0.0780781
Abstract
Growth hormone conjugated to Sepharose-4 B was found to mimic the action of the free hormone in the stimulation of the uptake and incorporation of radioactive uridine into RNA in thymocytes in vitro. The integrity of the cellular structure was essential for the stimulating effect of the hormone. The binding of the immunologically reactive determinants of the hormone on membranes of thymocytes was demonstrated by electron micrographs of preparations incubated sequentially with rabbit antigrowth hormone globulins and monospecific sheep anti-rabbit globulins tagged with horse-radish peroxidase.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to BioScientifica. |
| ID Code: | 52902 |
| Deposited On: | 04 Aug 2011 09:40 |
| Last Modified: | 12 Aug 2011 08:32 |
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