Veerapandian, B. ; Salunke, D. M. ; Vijayan, M. (1985) X-ray characterisation of an additional binding site in lysozyme FEBS Letters, 186 (2). pp. 163-167. ISSN 0014-5793
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Official URL: http://www.sciencedirect.com/science/article/pii/0...
Related URL: http://dx.doi.org/10.1016/0014-5793(85)80701-8
Abstract
Bromophenol red (BPR) binds to lysozyme and inhibits its activity against bacterial cell walls, but not against the polysaccharide component of peptidoglycan. The binding site of BPR in the enzyme has been characterised by X-ray analysis of the complex at 5.5Å resolution. The new binding site, which is outside the cleft close to subsite F, is presumably involved in interactions with the peptide component of peptidoglycan, in the action of lysozyme against bacterial cell walls.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Lysozyme; Bromophenol Red; X-ray Diffraction; UV Absorption; Additional Binding Site |
| ID Code: | 52537 |
| Deposited On: | 04 Aug 2011 07:48 |
| Last Modified: | 16 Jul 2012 05:31 |
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