Sharat Chandra, H. (1970) On X inactivation in XO embryos of mammals Genetical Research, 16 (2). pp. 233-234. ISSN 0016-6723
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Official URL: http://journals.cambridge.org/abstract_S0016672300...
Related URL: http://dx.doi.org/10.1017/S0016672300002469
Abstract
By analogy with the situation in coccids it is suggested that in mammalian XO embryos the single X turns heterochromatic in some cells, but that such a change does not result in cell death because the X then reverts back to an euchromatic and active state. This testable alternative to the Gartler-Sparkes hypothesis would imply that the anomalies of the XO Turner syndrome are largely due to imbalance of sex-linked genes rather than developmental damage resulting from cell death and that mammalian X inactivation might become reversed in response to special developmental needs.
Item Type: | Article |
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Source: | Copyright of this article belongs to Cambridge University Press. |
ID Code: | 5249 |
Deposited On: | 18 Oct 2010 07:23 |
Last Modified: | 09 Feb 2023 06:21 |
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