Sivapriya, Kirubakaran ; Suguna, Perumal ; Banerjee, Arun ; Saravanan, Vadivelu ; Rao, Desirazu N. ; Chandrasekaran, Srinivasan (2007) Facile one-pot synthesis of thio and selenourea derivatives: a new class of potent urease inhibitors Bioorganic & Medicinal Chemistry Letters, 17 (22). pp. 6387-6391. ISSN 0960-894X
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S09608...
Related URL: http://dx.doi.org/10.1016/j.bmcl.2007.07.085
Abstract
A facile, one-pot synthesis of thio and selenourea derivatives from amines using tetrathiomolybdate 1 and tetraselenotungstate 2 as sulfur and selenium transfer reagents, respectively, is reported. The compounds were tested for their activity as urease inhibitors and some of the compounds showed potent activity in the nanomolar range towards jack bean urease.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Thiourea; Selenourea; Urease Inhibition; Tetrathiomolybdate; Tetraselenotungstate |
| ID Code: | 51218 |
| Deposited On: | 28 Jul 2011 07:26 |
| Last Modified: | 13 Jul 2012 13:46 |
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