Bioenergetic consequences in the interaction of mammalian cell and virus for the multiplication of recombinant vaccinia and expression of heterologous protein (β-hCG)

Mukhopadhyay, Asok ; Mukhopadhyay, S. N. ; Talwar, G. P. (1994) Bioenergetic consequences in the interaction of mammalian cell and virus for the multiplication of recombinant vaccinia and expression of heterologous protein (β-hCG) Biotechnology Letters, 16 (4). pp. 339-344. ISSN 0141-5492

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Official URL: http://www.springerlink.com/content/y6080882jm7698...

Related URL: http://dx.doi.org/10.1007/BF00245047

Abstract

Energy generation in vaccinia virus infected Vero cell is investigated. The specific ATP pool in infected cells increases in the range of 40-80%, in contrast to uninfected cells. Virus replication and β-hCG expression are associated with the drop in ATP/ADP ratio from 7.0 to 2.5. High initial infection level leads to more energy generation and also more product formation.

Item Type:Article
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ID Code:50523
Deposited On:26 Jul 2011 13:04
Last Modified:26 Jul 2011 13:04

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