Chittari, Pabba ; Thomas, Achamma ; Rajappa, Srinivasachari (1994) Synthesis of novel cyclic hydroxamic acids Tetrahedron Letters, 35 (22). pp. 3793-3796. ISSN 0040-4039
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/S00404...
Related URL: http://dx.doi.org/10.1016/S0040-4039(00)73101-7
Abstract
The nitroacetyl (S)-proline esters (1,3,5) are reduced by zinc-NH4Cl to the hydroxylamine stage and cyclized to provide the novel chiral bicyclic hydroxamic acids (2,4,6). Michael addition of allyl acrylate on nitroacetic acid derivatives followed by Pd(0) catalyzed intramolecular allyl transfer and subsequent reduction of the nitro group yielded a novel class of cyclic hydroxamic acids related to pyroglutamic acid.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 50335 |
| Deposited On: | 23 Jul 2011 07:19 |
| Last Modified: | 23 Jul 2011 07:19 |
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