Naik, Sangeeta ; Renukaradhya, G. J. ; Rajasekhar, M. ; Shaila, M. S. (1997) Immunogenic and protective properties of haemagglutinin protein (H) of Rinderpest virus expressed by a recombinant baculovirus Vaccine, 15 (6-7). pp. 603-607. ISSN 0264-410X
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1016/S0264-410X(96)00244-7
Abstract
The hemagglutinin (H) protein of Rinderpest virus expressed by a recombinant baculo-virus used as a vaccine produced high titres of neutralizing antibody to Rinderpest virus in the vaccinated cattle, comparable to the levels produced by live attenuated vaccine. The immunized cattle were protected against a vaccine-virus challenge, as demonstrated by the failure of development of antibodies to N protein of the vaccine virus. The lack of replication of vaccine virus in the immunized cattle indicated that they are capable of showing a protective response if challenged with a virulent virus.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| Keywords: | Haemagglutinin; Rinderpest Virus; Recombinent Baculovirus; Protective Immunity |
| ID Code: | 49324 |
| Deposited On: | 20 Jul 2011 06:11 |
| Last Modified: | 20 Jul 2011 06:11 |
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