Panigrahi, D. ; Rotimi, V. O. ; Dhar, Rita ; Chugh, T. D. ; Dhar, P. M. ; Ghali, Adel ; Saad, Adel ; Sanyal, S. C. ; Varghese, T. L. (2001) Anaerobic bacterial flora of intra-abdominal infections and their antimicrobial susceptibility pattern in Kuwait Anaerobe, 7 (6). pp. 291-295. ISSN 1075-9964
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Official URL: http://www.sciencedirect.com/science/article/pii/S...
Related URL: http://dx.doi.org/10.1006/anae.2001.0404
Abstract
Clinical samples obtained from 200 patients with intra-abdominal infections were investigated for the presence of anaerobic bacteria. The majority of samples were from patients with appendicitis (108, 54%) followed by peritoneal abscess/peritonitis (37, 18.5%). A total of 153 anaerobes were isolated from 83 culture positive specimens with an isolation rate of 1.8 per sample. Ninety (59%) yielded Bacteroides fragilis group and B. fragilis stricto sensu accounted for half of them. Other isolates were 36 (23.5%) Prevotella species and 15 (9.8%)Peptostreptococcus micros . The susceptibility of the 153 isolates against eight antibiotics was determined by the E-test. All the isolates were susceptible to metronidazole, MIC90s varying between 1-2 μg/mL. ThePrevotella spp., Peptostreptococcus spp., Fusobacterium spp. and Porphyromonas spp. were all susceptible to clindamycin (MIC90s=0.25-2 μg/mL respectively), imipenem (MIC90s=0.12-0.5μg/mL respectively) and meropenem (MIC90=0.25 μg/mL each). About 25% of the B. fragilis group were resistant to clindamycin with MIC more than 256 μg/mL. Piperacillin-tazobactam also exhibited excellent in vitro activity against all the isolates (MIC90=0.25 μg/mL).
Item Type: | Article |
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Source: | Copyright of this article belongs to Elsevier Science. |
Keywords: | Intra-abdominal Infections; Anaerobic Bacteria; Antibiotic Susceptibility |
ID Code: | 49259 |
Deposited On: | 20 Jul 2011 06:38 |
Last Modified: | 20 Jul 2011 06:38 |
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