Sharma, Punita ; Asztalos, Zoltan ; Ayyub, Champakali ; De Bruyne, Marien ; Dornan, Anthony J. ; Gomez-Hernandez, Araceli ; Keane, John ; Killeen, James ; Kramer, Susanne ; Madhavan, Mayur ; Roe, Helen ; Sherkhane, Pradeep Dagadu ; Siddiqi, Khalid ; Silva, Elizabeth ; Carlson, John R. ; Goodwin, Stephen F. ; Heisenberg, Martin ; Krishnan, Kits ; Kyriacou, Charalambos P. ; Partridge, Linda ; Riesgo-escovar, Juan ; Rodrigues, Veronica ; Tully, Tim ; O'Kane, Cahir J. (2005) Isogenic autosomes to be applied in optimal screening for novel mutants with viable phenotypes in Drosophila melanogaster Journal of Neurogenetics, 19 (2). pp. 57-85. ISSN 0167-7063
Full text not available from this repository.
Official URL: http://informahealthcare.com/doi/abs/10.1080/01677...
Related URL: http://dx.doi.org/10.1080/01677060591007155
Abstract
Most insertional mutagenesis screens of Drosophila performed to date have not used target chromosomes that have been checked for their suitability for phenotypic screens for viable phenotypes. To address this, we have generated a selection of stocks carrying either isogenized second chromosomes or isogenized third chromosomes, in a genetic background derived from a Canton-S wild-type strain. We have tested these stocks for a range of behavioral and other viable phenotypes. As expected, most lines are statistically indistinguishable from Canton-S in most phenotypes tested. The lines generated are now being used as target chromosomes in mutagenesis screens, and the characterization reported here will facilitate their use in screens of these lines for behavioral and other viable phenotypes.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Informa plc. |
| Keywords: | Mutant Screens; Behavior; Learning; Canton-S Wild Type |
| ID Code: | 48380 |
| Deposited On: | 14 Jul 2011 06:43 |
| Last Modified: | 14 Jul 2011 06:43 |
Repository Staff Only: item control page
