Whaley, Kevin J. ; Sampath, D. S. ; Balaram, P. (1984) Optically active gossypol as a circular dichroism probe of interactions with serum albumins Biochimica et Biophysica Acta: General Subjects, 801 (1). pp. 127-130. ISSN 0304-4165
![]()
|
PDF
- Publisher Version
1MB |
Official URL: http://linkinghub.elsevier.com/retrieve/pii/030441...
Related URL: http://dx.doi.org/10.1016/0304-4165(84)90220-4
Abstract
The (+)-enantiomer of the polyphenolic binaphthyl gossypol, has been shown to be a useful CD probe of interactions with human and bovine serum albumin. (+)-Gossypol binds to albumin with same affinity as recemic (±)-gossypol, as shown by fluorescence quenching, and also displaces bilirubin from its albumin binding site. The CD characteristics of bound gossypol are different in the case of the two proteins.
Item Type: | Article |
---|---|
Source: | Copyright of this article belongs to Elsevier Science. |
Keywords: | Gossypol; CD; Albumin Interaction; Fluorescence Quenching |
ID Code: | 4760 |
Deposited On: | 18 Oct 2010 06:47 |
Last Modified: | 16 May 2016 15:22 |
Repository Staff Only: item control page