Saidapur, S. K. ; Nadkarni, V. B. (1975) The effect of 17 β -estradiol acetate on the testis and thumb pad of Rana cyanophlyctis (Schn.) and Rana tigrina (Daud.) General and Comparative Endocrinology, 27 (3). pp. 350-357. ISSN 0016-6480
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Official URL: http://linkinghub.elsevier.com/retrieve/pii/001664...
Related URL: http://dx.doi.org/10.1016/0016-6480(75)90202-6
Abstract
The effect of 17 β -estradiol acetate on the testis of two frogs Rana cyanophlyctis and Rana tigrina has been studied. 17 β -estradiol administration has an inhibitory action on spermatogenesis and also on Leydig cell secretory activity. There is a marked reduction in the Δ5-3 β -hydroxysteroid dehydrogenase (Δ5-3 β -HSDH) and glucose-6-phosphate dehydrogenase (G-6-PDH) activities in the Leydig cells accompanied by a marked rise in the free and the total cholesterol content of the testis. This suggests a reduction in androgen synthesis which is reflected in the regression of the androgen-dependent secondary sexual characters, the thumb pads.
| Item Type: | Article |
|---|---|
| Source: | Copyright of this article belongs to Elsevier Science. |
| ID Code: | 45298 |
| Deposited On: | 25 Jun 2011 15:01 |
| Last Modified: | 25 Jun 2011 15:01 |
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